Neurogenic muscle atrophy in myasthenia gravis
نویسندگان
چکیده
منابع مشابه
Neurogenic muscle atrophy in myasthenia gravis.
Two cases of severe myasthenia gravis are described, with histological findings. Both cases showed severe neurogenic atrophy of the muscles of the tongue, with fatty pseudohypertrophy and a remarkable proliferation of terminal nerve fibres. Similar, but less severe, changes were present in other bulbar muscles. The findings are in keeping with the view that functional interruption at the neurom...
متن کاملKey words: seronegative myasthenia gravis, muscle atrophy, muscle-specific receptor tyrosine kinase (MuSK) antibody, tongue atrophy Myasthenia gravis
Myasthenia gravis (MG) is an autoimmune disorder with easy fatigability of the muscles based on a neuromuscular transmission defect. Most myasthenic patients have antiacetylcholine receptor antibodies which attach to the acetycholine receptor of the postsynaptic membrane of the skeletal muscles and decrease the amplitude of miniature endplate potentials (mepp) and endplate potentials (epp) caus...
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A case of myasthenia gravis in a 15 years old girl is pre·sented. The disease was present for 5 years before thymectomy was performed. Indications for thymectomy, preoperative preparation, anesthetic and surgical management is -discussed.
متن کاملExtraocular muscle surgery in myasthenia gravis.
Myasthenia gravis is typically a disease of young people in active employment who need a field of binocular single vision. Although it is systemically controllable with a good chance of spontaneous remission, persistent loss of binocularity may cause chronic disability. We report our experience of extraocular muscle surgery in five patients with stable myasthenia gravis and persistent double vi...
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Myasthenia gravis is an autoimmune disorder of the neuromuscular junction. A number of molecules, including ion channels and other proteins at the neuromuscular junction, may be targeted by autoantibodies leading to abnormal neuromuscular transmission. In approximately 85% of patients, autoantibodies, directed against the postsynaptic nicotinic acetylcholine receptor can be detected in the seru...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1972
ISSN: 0022-3050
DOI: 10.1136/jnnp.35.3.311